Про рак (2 часть)

Originally posted by aquamarinka_30 at Про рак (2 часть)
The Quest for The Cures...Continues 11 episode docu-series.

Вредные воздействия, провоцирующие возникновение рака: (продолжение)

Séralini's experiment
Séralini designed his 2012 study as a direct followup of a previous study on the same NK603 maize conducted by Monsanto to support its application for regulatory authorization.
The overall experimental design was similar to Monsanto’s, in order to make the two experiments comparable. The differences were that Séralini’s experiment was longer (two years to Monsanto’s 90 days) and far more detailed in scope. Séralini’s experiment measured a larger number of health effects and was designed to separate out the effects of the GM maize from those of the herbicide it is engineered to tolerate, Roundup. This was the first study on a GM crop to distinguish effects in this way.
Séralini’s findings were alarming: both GM maize NK603 and Roundup caused serious kidney and liver damage and an increased and earlier development of tumours, leading to an increased rate of mortality.

These serious effects had not shown up in Monsanto’s 90-day test because it was too short. Serious diseases like organ damage and tumours take time to develop and become obvious.
from http://www.gmoseralini.org/faq-items/why-this-study-now/

Séralini’s study is the only long-term study on the commercialized GM maize NK603 and the pesticide (Roundup) it is designed to be grown with.
Séralini’s study showed that 90-day tests commonly done on GM foods are not long enough to see long-term effects like cancer, organ damage, and premature death. The first tumours only appeared 4-7 months into the study.
Long-term tests on GM foods are not required by regulators anywhere in the world
from http://www.gmoseralini.org/ten-things-you-need-to-know-about-the-seralini-study/

ГМО растения связаны с выработкой зонулина в кишечнике человека.
Zonulin - is the only physiological modulator of intercellular tight junctions described so far that is involved in trafficking of macromolecules and, therefore, in tolerance/immune response balance. When the finely tuned zonulin pathway is deregulated in genetically susceptible individuals, both intestinal and extraintestinal autoimmune, inflammatory, and neoplastic disorders can occur.

Another potential physiological role of intestinal zonulin is the protection against microorganism colonization of the proximal intestine (innate immunity)
Among the several potential intestinal luminal stimuli that can trigger zonulin release, we identified small intestinal exposure to bacteria and gluten as the two more powerful triggers.
A sytematic review of the literature revealed that HP precursor [that we identified as zonulin (159) and, therefore, the two terms can be used interchangeably] has been reported as a biomarker of several pathological conditions, including autoimmune diseases, diseases of the nervous system, and neoplastic conditions.

The classical paradigm of inflammatory pathogenesis involving specific genetic makeup and exposure to environmental triggers has been challenged recently by the addition of a third element, the loss of intestinal barrier function. Genetic predisposition, miscommunication between innate and adaptive immunity, exposure to environmental triggers, and loss of intestinal barrier function secondary to the activation of the zonulin pathway by food-derived environmental triggers or changes in gut microbiota all seem to be key ingredients involved in the pathogenesis of inflammation, autoimmunity, and cancer. This new theory implies that once the pathological process is activated, it is not auto-perpetuating. Rather, it can be modulated or even reversed by preventing the continuous interplay between genes and the environment. Since zonulin-dependent TJ dysfunction allows such interactions, new therapeutic strategies aimed at reestablishing the intestinal barrier function by downregulating the zonulin pathway offer innovative and not-yet-explored approaches for the management of these debilitating chronic diseases.
from http://physrev.physiology.org/content/91/1/151 -Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

Jeffrey Smith: It kills the beneficial bacteria, like bifidobacteria and lactobacillus, and it leaves the E. coli, salmonella and botulism intact. Now with that overgrowth of negative gut bacteria, it can produce zonulin, and zonulin can then result in the opening of the gaps in the cell walls of the intestines. So that’s one way that it can create gaps or leaky gut. Then you have BT toxin, which is found in the genetically engineered corn, and that produces holes in the cells directly because that’s how it kills insects, it’s an insecticide. They said “Oh, it’s not going to hurt humans,” but as it turns out, it pokes holes in the human cells in very much the same way, or it appears to.
from http://drpompa.com/additional-resources/health-tips/253-truth-about-gmos-jeffrey-smith-glyphosate

Jeffrey Smith: That list is among the things that are on the rise in the US population in parallel to the consumption of GMOs and it gets a little worse with BT toxin. We’re going to go on to herbicides in just a minute but I’ve got to land this blow. The BT toxin was found in the blood of 93% of the pregnant women tested in Canada, where you live and it was found in 80% of the unborn fetuses in the cord blood.

Now with mice that were … Mice blood cells which were exposed to BT toxin, the toxin was cytotoxic, damaging the red blood cells so now we have BT toxin circulating in our blood, possibly because it goes through the holes it created in the cell walls of the intestines and it might cause damage to the red blood cells. If it gets in the fetus, there’s no blood brain barrier yet developed so it might end up in the brain so you have hole poking toxins in the brain of the next generation.
Now, drum roll, please, or actually, you need the big drums hitting. Okay, what happens if you east corn chips from corn engineered to produce BT toxin and the genes from those corn chips transfers to the DNA of your gut bacteria and converts it into living pesticide trackers, that maybe why 93% of the pregnant women tested in Canada had BT toxin in their blood, because they were producing it in their gut.

And I've also found that Bt Toxin is approved for use on organic crops.
from https://www.bulletproofexec.com/jeffrey-smith-gmos-their-impact-on-health-178-transcript/

Round up используется в том числе as a ripening agent.

До этого свинец и мышьяк использовались на протяжении десятилетий в качестве пестицидов. Многие поля загрязнены ими.

Проблема с тяжелыми металлами в том, что они замещают собой в организме металлы, необходимы для метаболических процессов.

Продожение следует ...
Вот! А я никак не смогла расслышать это название в лекции Давида Перлмуттера на диабетическом саммите. Записала себе:

Gliadin induces breakdown of gut barrier, tight junctions that keep epithelial cells of gut lining. Gliadin stimulates production of chemical that leads to destabilization and deconstruction of these junctions.
Re: Zonulin
Статья, на которую я сослалась - http://physrev.physiology.org/content/9 1/1/151 -Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer - судя по всему, основополагающая. Ее многие цитируют.